MANY WAYS

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endocrine disruptors

Endocrine disruptors: exploring present challenges and future developments (in memory of Alfonso Lostia)

Currently, at EU level, scientific criteria for the identification of Endocrine Disruptors (EDs) are implemented only for pesticides and biocides. As highlighted by the Fitness Check of legislation on EDs, there is a need for a more horizontal approach to identifying EDs across different sectorial legislation, supported by strengthened information requirements. For EDs, screening of chemicals and decision-making is dominated by use of vertebrate data in general and, mammalian data, in particular. The session aims at giving emphasis to advancements in the field of EDs. It should serve as a platform for an open dialogue between regulatory and non-regulatory scientists to explore future possibilities to move to more integrated assessments. These would incorporate data generated by new technologies to reach better and faster decisions for more chemicals on a cross-sector basis, in line with the ‘one substance-one assessment’ ambitions within the Chemicals Strategy for Sustainability. Overall, the session outcome should help preparing for future challenges by putting shape on future directions and possible collaborations.

Session Coordinator

Session coordinator
Maria Arena (EFSA)

Session Contributors

Session contributors
Aude Kienzler (EFSA)
Sharon Munn (JRC)
Francesca Pellizzato (ECHA)
Andrea Terron (EFSA)

CONFIRMED PROGRAMME AFFILIATES

CHAIRPERSONS
Abstract Session Chairpersons
  • Martin Wilks, University of Basel 
  • Manuela Tiramani, European Food Safety Authority (EFSA)
SPEAKERS
Abstract Session Speakers
  • Andreas Kortenkamp, Brunel University - Endocrine Disruptors: challenges in the assessment and testing
  • Henrik Holbech, University of Southern Denmark - What works well and what needs improvement in ED assessments: academia perspective
  • Dan Pickford, Syngenta - What works well and what needs improvement in ED assessments: private sector perspective
  • Sander Van der Linden, European Chemical Agency (ECHA) - What works well and what needs improvement in ED assessments: EU agencies perspective
  • Emily McVey, Dutch Board for the Authorization of Plant Protection Products and Biocides (Ctgb) -   What works well and what needs improvement in ED assessments: competent authority perspective
  • Ninja Reineke, CHEM Trust - What works well and what needs improvement in ED assessments: NGO perspective
  • Karin Nienstedt/Jordane Wodli, Directorate-General for Health and Food Safety - Directorate-General for the Environment (European Commission) - What works well and what needs improvement in ED assessments: risk manager perspective
  • Donna Macmillan, Humane Society International (HSI) - Identifying endocrine disruptors - thoughts and recommendations for implementation in the EU
  • Lucia Vergauwen, University of Antwerp - Evaluation of an adverse outcome pathway network for thyroid hormone system disruption across taxonomic groups
  • Aldert Piersma, National Institute for Public Health and the Environment (RIVM) - Developing a quantitative AOP for liver-mediated thyroid modulation after prenatal exposure to a xenobiotic compound in the rat
  • Kevin Schlüppmann, Leibniz Research Institute of Environmental Medicine (IUF) - Redefining EDC hazard assessment by integrating an in vitro testing battery for endocrine disruptor (ED)-induced developmental neurotoxicity (DNT)
MODERATORS
Abstract Session Moderators
  • Andreas Kortenkamp, Brunel University 
  • Sharon Munn, Joint Research Centre (JRC)
PANELLISTS
Abstract Session Panellists
  • Cristina de Avila, Directorate-General for Health and Food Safety (European Commission) 
  • Henrik Holbech, University of Southern Denmark
  • Emily McVey, Dutch Board for the Authorization of Plant Protection Products and Biocides (Ctbg)
  • Karin Nienstedt, Directorate-General for Health and Food Safety (European Commission)
  • Dan Pickford, Syngenta
  • Ninja Reineke, CHEM Trust
  • Sander Van der Linden, European Chemical Agency (ECHA)
  • Jordane Wodli, Directorate-General for the Environment (European Commission)
RAPPORTEURS
Abstract Session Rapporteurs
  • Maria Arena, European Food Safety Authority (EFSA) 
  • Aude Kienzler, European Food Safety Authority (EFSA)
  • Francesca Pellizzato, European Chemicals Agency (ECHA)
  • Andrea Terron, European Food Safety Authority (EFSA)